Working out a loose plan

In Bogota now & working out what direction to go. Think I'm going South toward San Augustin & Mocoa for possible ayahuasca ceremony then head up toward Cali, Buga area then Medellin & continue up toward Cartegena, Santa Marta, Tayrona, etc. then head back South via Pamplona & Sierra Nevada del Cocoy and return to Bogota for my departure flight with possible extra excursion within a few hours from Bogota if I have time left.

By the map I'm not sure if I can easily get from San Augustin to Mocoa by bus? Anyone know?

Also, same question for Pamplona area to the Sierra Nevada del Cocoy. My guidebook only shows buses from Bogota. Can I get a bus from Pamplona to SN del Cocoy area?

This is still very loose but this route seems to cover pretty much most of the country. However, I'm not opposed to recalibrating and shortening route if I find places that beg for more time. :)